Sugi Predict

Sugi Predict / Compounds / SCHEMBL31455849

SCHEMBL31455849

SCHEMBL31455849

Cc1nc(NC(=O)c2ccc(C(=O)O)cc2)ccc1-n1c(-c2cccnc2N)nc2ccc(-c3ccccc3)cc21

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 12/20 0.46
▸ AKT2 P31751 8/20 0.44
▸ AKT3 Q9Y243 6/20 0.43
▸ MMP9 P14780 2/20 0.40
▸ GRM5 P41594 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ BTK Q06187 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31455851 1.00 AKT1 (0.46) AKT1AKT2AKT3MMP9GRM5
SCHEMBL31455947 0.93 AKT1 (0.44) AKT1AKT2AKT3MMP9GRM5
SCHEMBL31455265 0.85 AKT1 (0.45) AKT1AKT2AKT3
SCHEMBL31455126 0.83 AKT1 (0.43) AKT1AKT2AKT3
SCHEMBL31455477 0.79 AKT1 (0.46) AKT1AKT2AKT3
SCHEMBL31455860 0.77 AKT1 (0.47) AKT1AKT2AKT3
SCHEMBL31455703 0.76 AKT1 (0.48) AKT1AKT2AKT3
SCHEMBL31420329 0.75 AKT1 (0.50) AKT1AKT2AKT3
SCHEMBL31455914 0.74 AKT1 (0.48) AKT1AKT2AKT3
SCHEMBL31455657 0.73 AKT1 (0.65) AKT1AKT2AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059562-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME ATAVISTIK BIO, INC. (US) 2025-03-20 — — WO disclosed