Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726682 | 1.00 | KLKB1 (0.44) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL20446635 | 1.00 | KLKB1 (0.44) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL20584547 | 0.93 | KLKB1 (0.46) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL20446608 | 0.93 | KLKB1 (0.46) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL31456783 | 0.93 | KLKB1 (0.46) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL21726714 | 0.90 | KLKB1 (0.45) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL22685920 | 0.90 | KLKB1 (0.45) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL20446649 | 0.90 | KLKB1 (0.45) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL29489465 | 0.90 | KLKB1 (0.45) | KLKB1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL22685022 | 0.88 | KLKB1 (0.56) | KLKB1CYP1A2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591212-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2025-01-28 | — | — | CN | disclosed |