Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 12/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374582 | 1.00 | GRM4 (0.45) | GRM4PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL30751481 | 0.90 | DYRK1B (0.42) | GRM4PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL27375162 | 0.90 | DYRK1B (0.42) | GRM4PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL30751416 | 0.90 | GRM4 (0.48) | GRM4PTGDR2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31457074 | 0.89 | DYRK1B (0.42) | GRM4PTGDR2DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL30751276 | 0.88 | GRM4 (0.47) | GRM4PTGDR2NPC1RAB9A | |
| SCHEMBL31457020 | 0.88 | CYP17A1 (0.43) | GRM4 | |
| SCHEMBL27374758 | 0.88 | CYP17A1 (0.43) | GRM4 | |
| SCHEMBL31457015 | 0.87 | RIPK2 (0.40) | GRM4PTGDR2 | |
| SCHEMBL27375290 | 0.87 | RIPK2 (0.40) | GRM4PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |