SCHEMBL31457193

SCHEMBL31457193

COC(=O)C1=CC(=NO)CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 2/20 0.37
LMNA P02545 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
THRB P10828 1/20 0.36
CHRM1 P11229 1/20 0.36
PTPN1 P18031 1/20 0.36
BLM P54132 1/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
CA12 O43570 8/20 0.33
CA9 Q16790 8/20 0.33
TSHR P16473 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
MAPK10 P53779 1/20 0.32
KMT2A Q03164 1/20 0.32
PTK2B Q14289 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30543579 1.00 CHRM3 (0.37) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL30543578 1.00 CHRM3 (0.37) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL30543589 0.89 CHRM3 (0.35) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL30543590 0.89 CHRM3 (0.35) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL30543581 0.89 CHRM3 (0.35) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL2600399 0.75 CHRM3 (0.44) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL5906945 0.72 PTPN1 (0.50) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL1703562 0.72 CHRM3 (0.33) CHRM3HSD17B10
SCHEMBL1703563 0.72 CHRM3 (0.33) CHRM3HSD17B10
SCHEMBL2600393 0.68 CHRM3 (0.42) CHRM3LMNACHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640072-B Method for synthesizing oxime compound by catalyzing hydrocarbon bond oxidation through tetradentate nitrogen-containing coordination manganese 陕西师范大学 2025-02-28 CN disclosed