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SCHEMBL31458620

SCHEMBL31458620

Cc1n[nH]cc1-c1ccn2nc(NC3CCOCC3)nc2c1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 3/20 0.37
▸ MAPK1 P28482 12/20 0.36
▸ MAPK13 O15264 1/20 0.34
▸ MKNK1 Q9BUB5 1/20 0.34
▸ IRAK1 P51617 1/20 0.33
▸ MAPK8 P45983 1/20 0.33
▸ MAPK9 P45984 1/20 0.33
▸ MAPK10 P53779 1/20 0.33
▸ TTK P33981 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31458619 1.00 PIM1 (0.37) PIM1MAPK1MAPK13MKNK1IRAK1
SCHEMBL31458578 0.77 CDK2 (0.44) PIM1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31458616 0.76 MAPK1 (0.39) PIM1MAPK1MAPK13TTK
SCHEMBL31458604 0.75 MAPK8 (0.36) PIM1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31458626 0.74 AHR (0.43) PIM1MAPK1MKNK1MAPK8MAPK9
SCHEMBL31458606 0.73 PIM1 (0.33) PIM1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31458746 0.70 PDE1B (0.36) PIM1MAPK1MAPK8MAPK9MAPK10
SCHEMBL31458748 0.69 MAPK1 (0.35) PIM1MAPK1MKNK1MAPK8MAPK9
SCHEMBL31458682 0.67 IRAK4 (0.35) MAPK1
SCHEMBL26979104 0.67 MKNK1 (0.39) PIM1MAPK1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096061-A1 CDK2 INHIBITORS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed