Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31458743 | 0.85 | JAK2 (0.44) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL25226197 | 0.83 | JAK2 (0.43) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL25220733 | 0.83 | JAK2 (0.43) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31423892 | 0.78 | JAK2 (0.43) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL31423994 | 0.78 | JAK2 (0.39) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL25673249 | 0.74 | JAK2 (0.38) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL23209287 | 0.74 | JAK2 (0.42) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL23209255 | 0.74 | JAK2 (0.42) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL12066113 | 0.73 | JAK2 (0.54) | JAK2JAK1TYK2JAK3MAP3K5 | |
| SCHEMBL23209356 | 0.71 | JAK2 (0.43) | JAK2JAK1TYK2JAK3MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096061-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |