Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 10/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 5/20 | 0.33 |
| ▸ | CCND1 | P24385 | 5/20 | 0.33 |
| ▸ | CCND3 | P30281 | 5/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31423917 | 0.90 | JAK2 (0.39) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL25272284 | 0.90 | JAK2 (0.36) | JAK2JAK1TYK2JAK3MAPK1 | |
| SCHEMBL31458686 | 0.88 | JAK2 (0.35) | JAK2JAK1TYK2JAK3MAPK1 | |
| SCHEMBL31458719 | 0.87 | JAK2 (0.34) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL25261220 | 0.86 | JAK2 (0.36) | JAK2JAK1TYK2JAK3MAPK1 | |
| SCHEMBL31458716 | 0.86 | JAK2 (0.34) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL31458579 | 0.83 | JAK2 (0.36) | JAK2JAK1TYK2JAK3MAPK1 | |
| SCHEMBL25226135 | 0.81 | CD274 (0.39) | JAK2JAK1TYK2JAK3MAPK1 | |
| SCHEMBL31423918 | 0.80 | JAK2 (0.41) | JAK2JAK1TYK2JAK3CD274 | |
| SCHEMBL25422687 | 0.80 | JAK2 (0.35) | JAK2JAK1TYK2JAK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096061-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |