SCHEMBL31458873

SCHEMBL31458873

CC1CC(c2cc(Cl)nc(OC3CC3)c2)(c2nncn2C)C1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.44
▸ CBL P22681 16/20 0.41
▸ CBLC Q9ULV8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31251387 0.88 CBLB (0.46) CBLBCBLCBLC
SCHEMBL31274922 0.87 CBLB (0.47) CBLBCBL
SCHEMBL31275077 0.86 CBLB (0.35) CBLBCBLCBLC
SCHEMBL25413018 0.86 CBLB (0.48) CBLBCBLCBLC
SCHEMBL25413016 0.86 CBLB (0.48) CBLBCBLCBLC
SCHEMBL31549955 0.84 CBLB (0.42) CBLBCBL
SCHEMBL30184959 0.82 CBLB (0.52) CBLBCBLCBLC
SCHEMBL30184958 0.82 CBLB (0.52) CBLBCBLCBLC
SCHEMBL31459392 0.81 CBLB (0.41) CBLBCBLCBLC
SCHEMBL31015521 0.81 CBLB (0.50) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067227-A1 PREPARATION METHOD FOR CBL-B REGULATOR, AND USE 浙江华海药业股份有限公司 2025-04-03 — — WO disclosed
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