Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3780151 | 0.99 | KDM1A (0.44) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| SCHEMBL3151899 | 0.91 | KDM1A (0.44) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| Hydrochloric Acid SCHEMBL3843137 | 0.90 | KDM1A (0.44) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| SCHEMBL3141651 | 0.89 | KDM1A (0.56) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| SCHEMBL3137179 | 0.88 | CYP1A2 (0.40) | KDM1A | |
| SCHEMBL3151443 | 0.88 | KDM1A (0.43) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| Hydrochloric Acid SCHEMBL3778970 | 0.88 | KDM1A (0.55) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| Hydrochloric Acid SCHEMBL3776431 | 0.87 | CYP1A2 (0.40) | KDM1A | |
| Hydrochloric Acid SCHEMBL3779588 | 0.87 | KDM1A (0.42) | KDM1AMAOBAKT1KCNH2RCOR1 | |
| Hydrochloric Acid SCHEMBL3778995 | 0.84 | CHRNB4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |