SCHEMBL31459418

SCHEMBL31459418

COCc1cc(C2(c3nncn3C)CC(C)C2)cc(Cl)n1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.44
▸ CBL P22681 17/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25413016 0.86 CBLB (0.48) CBLBCBL
SCHEMBL25413018 0.86 CBLB (0.48) CBLBCBL
SCHEMBL31459557 0.84 CBLB (0.31) CBLB
SCHEMBL31251387 0.83 CBLB (0.46) CBLBCBL
SCHEMBL30184958 0.82 CBLB (0.52) CBLBCBL
SCHEMBL30184959 0.82 CBLB (0.52) CBLBCBL
SCHEMBL25413553 0.80 CBLB (0.44) CBLBCBL
SCHEMBL25413551 0.80 CBLB (0.44) CBLBCBL
SCHEMBL31274922 0.80 CBLB (0.47) CBLBCBL
SCHEMBL31549955 0.80 CBLB (0.42) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067227-A1 PREPARATION METHOD FOR CBL-B REGULATOR, AND USE 浙江华海药业股份有限公司 2025-04-03 — — WO disclosed
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