Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 9/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 9/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 14/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 14/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.35 |
| ▸ | CHRNG | P07510 | 2/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.35 |
| ▸ | CHRND | Q07001 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31460270 | 1.00 | CHRNB4 (0.42) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL20827756 | 0.82 | MAP3K14 (0.33) | — | |
| SCHEMBL5390017 | 0.82 | — | — | |
| SCHEMBL2484399 | 0.77 | DAO (0.32) | — | |
| SCHEMBL27115171 | 0.77 | — | — | |
| SCHEMBL10351130 | 0.72 | DAO (0.32) | — | |
| SCHEMBL1748458 | 0.71 | HTR2A (0.32) | — | |
| SCHEMBL1748796 | 0.71 | HTR2A (0.32) | — | |
| SCHEMBL4248559 | 0.69 | CHRNB4 (0.38) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL5386313 | 0.69 | DAO (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |