Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 8/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | TIPARP | Q7Z3E1 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 6/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859861 | 1.00 | PANK3 (0.59) | PANK3RETTIPARPCHRM1CNR2 | |
| SCHEMBL30860008 | 0.90 | PANK3 (0.57) | PANK3TIPARPCHRM1PARP1PARP2 | |
| SCHEMBL31464937 | 0.90 | PANK3 (0.57) | PANK3TIPARPCHRM1PARP1PARP2 | |
| SCHEMBL31464914 | 0.87 | PANK3 (0.54) | PANK3TIPARPCHRM1CNR2PARP1 | |
| SCHEMBL30859828 | 0.87 | PANK3 (0.54) | PANK3TIPARPCHRM1CNR2PARP1 | |
| SCHEMBL21521591 | 0.85 | PANK3 (0.54) | PANK3RETTIPARPCHRM1CNR2 | |
| SCHEMBL21520947 | 0.82 | PANK3 (0.55) | PANK3TIPARPCHRM1PARP1PARP2 | |
| SCHEMBL30546362 | 0.82 | PANK3 (0.63) | PANK3RETCNR2 | |
| SCHEMBL3554489 | 0.82 | PANK3 (0.63) | PANK3RETCNR2 | |
| SCHEMBL31464986 | 0.81 | PANK3 (0.57) | PANK3RETTIPARPCNR2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968364-A | Pyridazin-3 (2H) -one and pyridin-2 (1H) -one PARP inhibitor compounds | 阿兹卡拉疗法公司 | 2025-05-09 | — | — | CN | disclosed |