Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19455177 | 0.85 | MAPT (0.59) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL11605087 | 0.85 | KDM4E (0.57) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL31465402 | 0.81 | MAPT (0.61) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL12953199 | 0.81 | MAPT (0.56) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL12953072 | 0.80 | PDE10A (0.46) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL20971704 | 0.79 | MAPT (0.54) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL17732308 | 0.78 | KDM4E (0.71) | KDM4EMAPTRAB9AALDH1A1HPGD | |
| SCHEMBL18343698 | 0.78 | KDM4E (0.59) | KDM4EMAPTRAB9AALDH1A1HPGD | |
| SCHEMBL7436122 | 0.77 | KDM4E (0.38) | KDM4EMAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL3188128 | 0.76 | MAPT (0.62) | KDM4EMAPTRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068090-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2025-04-03 | — | — | WO | disclosed |