Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.43 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22325269 | 0.99 | EPHX2 (0.45) | EPHX2TLR8ACKR3KMT5APAOX | |
| SCHEMBL22325407 | 0.99 | EPHX2 (0.45) | EPHX2TLR8ACKR3KMT5APAOX | |
| SCHEMBL29290835 | 0.99 | EPHX2 (0.45) | EPHX2TLR8ACKR3KMT5APAOX | |
| SCHEMBL21068826 | 0.96 | TLR8 (0.46) | EPHX2TLR8ACKR3KMT5AUSP2 | |
| SCHEMBL5883993 | 0.90 | SMN1; SMN2 (0.48) | EPHX2TLR8ACKR3USP2SMN1; SMN2 | |
| SCHEMBL22608846 | 0.87 | USP2 (0.46) | EPHX2TLR8ACKR3USP2SMN1; SMN2 | |
| SCHEMBL8253901 | 0.86 | USP2 (0.51) | EPHX2TLR8ACKR3KMT5AUSP2 | |
| SCHEMBL21069069 | 0.86 | TLR8 (0.46) | EPHX2TLR8ACKR3USP2SMN1; SMN2 | |
| SCHEMBL25397689 | 0.85 | EPHX2 (0.45) | EPHX2TLR8ACKR3USP2SMN1; SMN2 | |
| SCHEMBL1715432 | 0.85 | TLR8 (0.45) | EPHX2TLR8ACKR3PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049555-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-03-06 | — | — | WO | disclosed |