Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435294 | 0.89 | SCN3A (0.47) | SCN3ASCN5ASCN9ACNR1CNR2 | |
| SCHEMBL24434687 | 0.88 | SCN3A (0.45) | SCN3ASCN5ASCN9ACNR1CNR2 | |
| SCHEMBL24434845 | 0.87 | SMN1; SMN2 (0.45) | SCN3ASCN5ASCN9ACNR1CNR2 | |
| SCHEMBL24434576 | 0.86 | SCN3A (0.48) | SCN3ASCN5ASCN9AMAPTCNR1 | |
| SCHEMBL24434808 | 0.86 | KDM4E (0.40) | SCN3ASCN5ASCN9AMAPTCNR1 | |
| SCHEMBL24434967 | 0.84 | NPC1 (0.44) | SCN3ASCN5ASCN9AMAPTCNR1 | |
| SCHEMBL24435288 | 0.84 | CNR2 (0.39) | SCN3ASCN5ASCN9ACNR1CNR2 | |
| SCHEMBL24434544 | 0.84 | CNR2 (0.41) | SCN3ASCN5ASCN9AMAPTCNR1 | |
| SCHEMBL24435088 | 0.83 | NPC1 (0.41) | SCN3ASCN5ASCN9AMAPTCNR1 | |
| SCHEMBL24434540 | 0.83 | SCN3A (0.41) | SCN3ASCN5ASCN9ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3930849-B1 | THIAZOLE DERIVATIVES AS PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2025-02-19 | — | — | EP | disclosed |