SCHEMBL31467232

SCHEMBL31467232

O=C(NS(=O)(=O)c1ccc(NCC2CCOCC2)c([N+](=O)[O-])c1)c1ccc(N2CCC3(CC2)CN(C2CCc4cc(Cl)ccc42)C3)cc1Oc1cnc2[nH]ccc2c1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 20/20 0.76
▸ BCL2L1 Q07817 14/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31011836 0.92 BCL2 (0.75) BCL2BCL2L1
SCHEMBL29328469 0.92 BCL2 (0.75) BCL2BCL2L1
SCHEMBL31011823 0.91 BCL2 (0.79) BCL2BCL2L1
SCHEMBL29329395 0.91 BCL2 (0.79) BCL2BCL2L1
SCHEMBL29329383 0.91 BCL2 (0.78) BCL2BCL2L1
SCHEMBL31011877 0.91 BCL2 (0.78) BCL2BCL2L1
SCHEMBL31011889 0.89 BCL2 (0.78) BCL2BCL2L1
SCHEMBL29329378 0.89 BCL2 (0.78) BCL2BCL2L1
SCHEMBL31467013 0.89 BCL2 (0.77) BCL2BCL2L1
SCHEMBL31011978 0.89 BCL2 (0.77) BCL2BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064952-A1 BCL-2 INHIBITORS Eil Therapeutics, Inc. (US) 2025-03-27 — — WO disclosed
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