Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20250802 | 0.85 | SLC6A2 (0.49) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| SCHEMBL2625762 | 0.81 | SLC6A2 (0.50) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| Iodide SCHEMBL29267965 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| SCHEMBL13209528 | 0.76 | SLC6A2 (0.50) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| SCHEMBL16685072 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4NOTUMCNR2SLC6A3 | |
| SCHEMBL5848485 | 0.75 | SLC6A2 (0.56) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| SCHEMBL16684820 | 0.74 | SLC6A2 (0.45) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| SCHEMBL15523054 | 0.73 | NOTUM (0.40) | SLC6A2SLC6A4NOTUMHTR2AHTR2C | |
| SCHEMBL16685074 | 0.72 | SLC6A2 (0.49) | SLC6A2SLC6A4NOTUMCNR2HTR2C | |
| SCHEMBL5472708 | 0.71 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049643-A1 | NOX4 INHIBITORS AND METHODS OF MAKING AND USING SAME | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2025-03-06 | — | — | WO | disclosed |