Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.72 |
| ▸ | GAA | P10253 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | GFER | P55789 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20956983 | 0.90 | MAPT (0.67) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL31467502 | 0.90 | MAPT (0.60) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20957008 | 0.90 | MAPT (0.59) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20957034 | 0.88 | MAPT (0.68) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20988233 | 0.87 | MAPT (0.56) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL31467489 | 0.87 | MAPT (0.56) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20956979 | 0.87 | MAPT (0.56) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL30541980 | 0.85 | MAPT (0.55) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20957051 | 0.85 | MAPT (0.55) | MAPTGAATP53GFERL3MBTL1 | |
| SCHEMBL20957004 | 0.85 | MAPT (0.58) | MAPTGAATP53GFERL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049643-A1 | NOX4 INHIBITORS AND METHODS OF MAKING AND USING SAME | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2025-03-06 | — | — | WO | disclosed |