Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31468374 | 0.89 | PARP1 (0.49) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3299464 | 0.84 | NPC1 (0.61) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31468434 | 0.84 | MEN1 (0.49) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16770357 | 0.83 | KDM4E (0.55) | PARP1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL13297993 | 0.83 | PARP1 (0.49) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15191719 | 0.83 | PARP1 (0.57) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4707821 | 0.82 | ERCC1 (0.48) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12290398 | 0.79 | PARP1 (0.53) | PARP1KDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL12953145 | 0.79 | ERCC1 (0.50) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31468352 | 0.77 | KDM5A (0.43) | PARP1MAPTCDC7MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064210-A1 | INHIBITORS OF BILIVERDIN REDUCTASE B (BLVRB) | BLOOD CELL TECHNOLOGIES, LLC (US) | 2025-03-27 | — | — | WO | disclosed |