SCHEMBL31468547

SCHEMBL31468547

C=Cc1cccc([Si](C)(C)CCCN(CCCC)CCCC)c1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
DRD2 P14416 3/20 0.35
OPRM1 P35372 3/20 0.35
DRD3 P35462 3/20 0.35
OPRD1 P41143 3/20 0.35
OPRK1 P41145 3/20 0.35
HTR1B P28222 1/20 0.32
ATP4A P20648 4/20 0.32
ATP4B P51164 4/20 0.32
BCHE P06276 2/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
ACHE P22303 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468513 0.90 TP53 (0.37) TP53TDP1OPRM1DRD3ATP4A
SCHEMBL31468648 0.88 TP53 (0.37) TP53TDP1DRD2OPRM1DRD3
SCHEMBL713836 0.86 TDP1 (0.40) TP53TDP1NR1H2NR1H3
SCHEMBL31468582 0.85 TP53 (0.39) TP53TDP1
SCHEMBL31468605 0.83 TP53 (0.33) TP53TDP1DRD2OPRM1DRD3
SCHEMBL31468642 0.83 NR1H2 (0.40) ATP4AATP4BNR1H2NR1H3
SCHEMBL31468667 0.82 TP53 (0.33) TP53TDP1DRD2OPRM1DRD3
SCHEMBL610103 0.79 TP53 (0.39) TP53TDP1HTT
SCHEMBL16032677 0.79 TP53 (0.39) TP53TDP1HTT
SCHEMBL29514996 0.79 TP53 (0.39) TP53TDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 TP53 3489/4885TDP1 4654/4885DRD2 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.