SCHEMBL31468617

SCHEMBL31468617

C=C(c1ccccc1)c1ccc([Si](CN(C)C)(OC)OC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
EGFR P00533 5/20 0.37
GRM2 Q14416 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HIF1A Q16665 1/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
ESR1 P03372 2/20 0.32
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
CYP2D6 P10635 2/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
NR1I2 O75469 1/20 0.31
PRKD3 O94806 1/20 0.31
ABCB11 O95342 1/20 0.31
GBA1 P04062 1/20 0.31
NR3C1 P04150 1/20 0.31
ERBB2 P04626 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468625 0.86 MEN1 (0.43) MEN1KMT2AEGFRESR1HTR2A
SCHEMBL31468522 0.85 MEN1 (0.45) MEN1KMT2AEGFRGRM2ALDH1A1
SCHEMBL31468476 0.85 KMT2A (0.41) MEN1KMT2AEGFRGRM2ALDH1A1
SCHEMBL28614693 0.83 MEN1 (0.43) MEN1KMT2AGRM2ALDH1A1ESR1
SCHEMBL31468644 0.81 MEN1 (0.38) MEN1KMT2AGRM2NR1I2DRD2
SCHEMBL31468659 0.80 MEN1 (0.51) MEN1KMT2AEGFRGRM2ALDH1A1
SCHEMBL31468504 0.75 MEN1 (0.41) MEN1KMT2AEGFRALDH1A1ESR1
SCHEMBL31468568 0.75 KMT2A (0.38) MEN1KMT2AEGFRALDH1A1ESR1
SCHEMBL28630100 0.75 MEN1 (0.48) MEN1KMT2AGRM2MAOAMAOB
SCHEMBL28618666 0.74 MEN1 (0.47) MEN1KMT2AGRM2ESR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 MEN1 617/4885KMT2A 1539/4885EGFR 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.