SCHEMBL31468632

SCHEMBL31468632

C=C(c1ccccc1)c1ccc([Si](C)(C)CCCN(CCCC)CCCC)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
DRD2 P14416 2/20 0.37
DRD3 P35462 2/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
DRD4 P21917 1/20 0.37
NR1I2 O75469 1/20 0.36
BCHE P06276 4/20 0.36
ACHE P22303 2/20 0.36
GRM2 Q14416 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468650 0.90 KMT2A (0.41) NR1H2NR1H3MEN1KMT2ADRD3
SCHEMBL31468622 0.88 MEN1 (0.41) MEN1KMT2ADRD2DRD3OPRM1
SCHEMBL31468562 0.85 KMT2A (0.46) MEN1KMT2A
SCHEMBL31468517 0.83 MEN1 (0.37) MEN1KMT2ADRD2DRD3OPRM1
SCHEMBL31468459 0.82 MEN1 (0.36) MEN1KMT2ADRD2DRD3OPRM1
SCHEMBL19125392 0.80 MEN1 (0.44) MEN1KMT2ANR1I2GRM2GAA
SCHEMBL16033355 0.80 MEN1 (0.44) MEN1KMT2ANR1I2GRM2GAA
SCHEMBL16033157 0.77 MEN1 (0.47) MEN1KMT2ANR1I2GRM2GAA
SCHEMBL31468644 0.76 MEN1 (0.38) MEN1KMT2ADRD2DRD3OPRM1
SCHEMBL609298 0.76 MAPT (0.54) MEN1KMT2ABCHENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 NR1H2 72/4885NR1H3 53/4885MEN1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.