Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.41 |
| ▸ | STK4 | Q13043 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26585005 | 0.83 | MAPT (0.52) | MAPTEGFRSMN1; SMN2RECQLKDM4E | |
| SCHEMBL31469220 | 0.81 | MAPT (0.45) | MAPTEGFRSMN1; SMN2RECQLKDM4E | |
| SCHEMBL38651210 | 0.78 | CAMKK1 (0.39) | EGFRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL26111167 | 0.76 | EGFR (0.43) | EGFRKDM4EALDH1A1GAAERBB4 | |
| SCHEMBL26113555 | 0.74 | EGFR (0.48) | MAPTEGFRKDM4EALDH1A1GAA | |
| SCHEMBL31469333 | 0.74 | EGFR (0.43) | EGFRKDM4EALDH1A1GAAERBB4 | |
| SCHEMBL31469351 | 0.74 | GSK3B (0.46) | EGFRKDM4EALDH1A1GAAERBB4 | |
| SCHEMBL26110822 | 0.72 | EGFR (0.62) | EGFRERBB4ERBB2 | |
| SCHEMBL26113885 | 0.71 | CSNK1D (0.41) | MAPTEGFR | |
| SCHEMBL26111424 | 0.69 | CSNK1D (0.43) | MAPTEGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |