Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.60 |
| ▸ | ILK | Q13418 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | GAK | O14976 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836608 | 0.83 | EGFR (0.60) | EGFRGAKENPP1LCKSRC | |
| SCHEMBL31469346 | 0.77 | EGFR (0.59) | EGFRKDR | |
| SCHEMBL6180450 | 0.75 | EGFR (1.00) | EGFRLCKRETKDR | |
| SCHEMBL31469329 | 0.75 | EGFR (0.59) | EGFRENPP1LCKSRCRIPK2 | |
| SCHEMBL1985538 | 0.74 | LCK (0.66) | EGFRGAKENPP1LCKSRC | |
| SCHEMBL1260737 | 0.74 | ENPP1 (0.54) | EGFRGAKALDH1A1ENPP1LCK | |
| SCHEMBL23726845 | 0.73 | ENPP1 (0.53) | EGFRGAKENPP1LCKSRC | |
| SCHEMBL3166753 | 0.73 | PDE5A (0.57) | EGFRGAKENPP1LCKSRC | |
| SCHEMBL2476964 | 0.73 | RET (0.55) | EGFRGAKENPP1LCKSRC | |
| SCHEMBL19933282 | 0.73 | ENPP1 (0.53) | EGFRGAKENPP1LCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |