Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 8/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 7/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19273914 | 0.91 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL17730210 | 0.88 | CYP2C19 (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL30852394 | 0.88 | CYP2C19 (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL29407981 | 0.88 | CYP2C19 (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL24380208 | 0.84 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL31520053 | 0.84 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL30852333 | 0.84 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL30852267 | 0.84 | KDM4E (0.54) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL12319246 | 0.83 | KDM4E (0.52) | KDM4EHIF1ATDP1SLC1A1SLC1A3 | |
| SCHEMBL16801822 | 0.82 | KDM4E (0.51) | KDM4EHIF1ATDP1SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250044306-A1 | Methods for Determining Opioid Responsiveness in the Treatment of Pain | EAST CAROLINA UNIVERSITY | 2025-02-06 | — | — | US | disclosed |