Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25143840 | 0.87 | CRBN (0.48) | CRBNDDB1POLB | |
| SCHEMBL30201703 | 0.87 | CRBN (0.48) | CRBNDDB1POLB | |
| SCHEMBL30851413 | 0.87 | CRBN (0.48) | CRBNDDB1POLB | |
| SCHEMBL24670099 | 0.87 | CRBN (0.48) | CRBNDDB1POLB | |
| SCHEMBL25143839 | 0.87 | CRBN (0.48) | CRBNDDB1POLB | |
| SCHEMBL31470511 | 0.84 | CRBN (0.43) | CRBNDDB1POLB | |
| SCHEMBL25219414 | 0.83 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL25074541 | 0.83 | CRBN (0.46) | CRBNDDB1POLB | |
| SCHEMBL30201974 | 0.83 | CRBN (0.46) | CRBNDDB1POLB | |
| SCHEMBL24670592 | 0.82 | CRBN (0.45) | CRBNDDB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070287-A | IRAK 4-targeted degradation agent compound and application thereof | 江苏先声药业有限公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-2025077891-A1 | DEGRADATION AGENT COMPOUND TARGETING IRAK4, AND USE THEREOF | 江苏先声药业有限公司 | 2025-04-17 | — | — | WO | disclosed |