SCHEMBL31470959

SCHEMBL31470959

C[Si](C)(C)C#CC(O)COc1cc(-c2ccc(F)nc2)c2c(C#N)cnn2c1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RET P07949 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31470962 1.00 RET (0.50) RET
SCHEMBL20069345 0.87 RET (0.62) RET
SCHEMBL29596795 0.87 RET (0.62) RET
SCHEMBL20069936 0.87 RET (0.62) RET
SCHEMBL20069940 0.87 RET (0.62) RET
SCHEMBL29686294 0.87 RET (0.62) RET
SCHEMBL20906317 0.86 RET (0.62) RET
SCHEMBL20068897 0.82 RET (0.66) RET
SCHEMBL29971635 0.82 RET (0.66) RET
SCHEMBL20069346 0.81 RET (0.64) RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683610-B RET inhibitor, pharmaceutical composition and application thereof 广东东阳光药业股份有限公司 2025-02-25 CN disclosed