SCHEMBL314712

SCHEMBL314712

O=Cc1cn[nH]c1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24688553 0.73
SCHEMBL21670037 0.71
SCHEMBL1844112 0.71
SCHEMBL3259059 0.71
SCHEMBL4505993 0.71
SCHEMBL15112518 0.71 PDPK1 (0.44)
SCHEMBL17754596 0.70 PDPK1 (0.38)
SCHEMBL29954167 0.70 PDPK1 (0.57)
SCHEMBL1845422 0.67
SCHEMBL4058838 0.67 SLC2A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301787-A2 METHOD FOR DETECTING URACIL BIOSYNTHESIS INHIBITORS AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-04-16 EP claimed
US-20020058244-A1 Method for detecting uracil biosynthesis inhibitors and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2002-05-16 US claimed
WO-2002006512-A2 METHOD FOR DETECTING URACIL BIOSYNTHESIS INHIBITORS AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-01-24 WO claimed
US-8093251-B2 Nitrogen-containing heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-8026368-B2 Hydrazide compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-27 US disclosed
US-20090253751-A1 HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-08 US disclosed
US-20090198060-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-06 US disclosed
EP-2025671-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR Nissan Chemical Industries, Ltd. (JP) 2009-02-18 EP disclosed
EP-1947101-A1 HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR Nissan Chemical Industries, Ltd. (JP) 2008-07-23 EP disclosed
CN-1090619-C Process for preparing 1-alkyl-4-(2-chloro-3-alkoxy-4-alkylsulfonylbenzoyl)-5-hydroxypyrazole and related compounds DOW AGROSCIENCES LLC (US) 2002-09-11 CN disclosed
CN-1224419-A Process for preparing 1-alkyl-4-(2-chloro-3-alkoxy-4-alkylsulfonylbenzoyl)-5-hydroxypyrazole and related compounds DOW AGROSCIENCES LLC (US) 1999-07-28 CN disclosed
EP-0775136-A1 5-HYDROXYPYRAZOL-4-YL-CARBONYL-SUBSTITUTED SACCHARIN DERIVATIVES WITH HERBICIDAL PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1997-05-28 EP disclosed
WO-1996005197-A1 5-HYDROXYPYRAZOL-4-YL-CARBONYL-SUBSTITUTED SACCHARIN DERIVATIVES WITH HERBICIDAL PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1996-02-22 WO disclosed