Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3155887 | 0.91 | FFAR4 (0.36) | FFAR4 | |
| SCHEMBL3147342 | 0.89 | MAP4K4 (0.37) | FFAR4MAP4K4 | |
| SCHEMBL3137025 | 0.89 | SMN1; SMN2 (0.36) | ABL1MAP4K4 | |
| SCHEMBL3257000 | 0.88 | FFAR4 (0.42) | FFAR4MAP4K4 | |
| SCHEMBL3151386 | 0.88 | CYP11B1 (0.36) | CYP4A11CYP4F2 | |
| SCHEMBL3141821 | 0.87 | KDM1A (0.41) | MAP4K4 | |
| SCHEMBL3145775 | 0.84 | CYP11B1 (0.40) | — | |
| SCHEMBL3151465 | 0.82 | ABL1 (0.35) | ABL1MAP4K4 | |
| SCHEMBL3151018 | 0.81 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL3260962 | 0.80 | PTGDR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |