Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456427 | 1.00 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL21491223 | 1.00 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL31472366 | 0.92 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL21491100 | 0.92 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL21491447 | 0.87 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL21491395 | 0.86 | TSHR (0.42) | HSP90AA1HSP90AB1ALDH1A1TSHRLMNA | |
| SCHEMBL29849135 | 0.86 | TSHR (0.42) | HSP90AA1HSP90AB1ALDH1A1TSHRLMNA | |
| SCHEMBL31472357 | 0.85 | TSHR (0.42) | ALDH1A1TSHRLMNAUSP30MEN1 | |
| SCHEMBL21491471 | 0.85 | TSHR (0.42) | ALDH1A1TSHRLMNAUCHL1USP30 | |
| SCHEMBL21491116 | 0.85 | TSHR (0.42) | ALDH1A1TSHRLMNAUSP30MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-B | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2025-04-01 | — | — | CN | disclosed |