Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD known ✓ | Q03181 | 6/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL22729316 | 1.00 | GSR (0.67) | GSRFFAR4FFAR1AKR1B1CYP2D6 | |
| Decanoic Acid SCHEMBL597983 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Myristic Acid SCHEMBL2909091 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Stearic Acid SCHEMBL7176001 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Decanoic Acid SCHEMBL6374907 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| SCHEMBL18344245 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Octanoic Acid SCHEMBL7178164 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Octanoic Acid SCHEMBL7178169 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Palmitic Acid SCHEMBL597984 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 | |
| Decanoic Acid SCHEMBL6374906 | 0.98 | GSR (0.65) | GSRFFAR4FFAR1ALDH1A1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775362-A | High-efficiency low-toxicity anticancer short peptide using caproic acid lysine as modification unit and application thereof | 兰州大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119775362-A | High-efficiency low-toxicity anticancer short peptide using caproic acid lysine as modification unit and application thereof | 兰州大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775362-A | High-efficiency low-toxicity anticancer short peptide using caproic acid lysine as modification unit and application thereof | 兰州大学 | 2025-04-08 | — | — | CN | disclosed |