Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | FLT1 | P17948 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 11/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KIF5B | P33176 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22983424 | 1.00 | KDR (0.50) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL5097637 | 0.92 | KDR (0.60) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL4577834 | 0.91 | SRC (0.56) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL22983867 | 0.90 | KDR (0.47) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL29719135 | 0.90 | RAF1 (0.51) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL22983725 | 0.90 | RAF1 (0.51) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL29718942 | 0.90 | KDR (0.47) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL4579884 | 0.87 | KDR (0.50) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL3239502 | 0.87 | EGFR (0.59) | KDRFLT1FGFR1EPHB2FLT4 | |
| SCHEMBL157980 | 0.86 | EGFR (0.50) | KDRFLT1FGFR1EPHB2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079960-A | Alkynyl quinazoline compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-119390683-A | Alkynyl quinazoline compounds | 黑钻治疗公司 | 2025-02-07 | — | — | CN | disclosed |