SCHEMBL31473001

SCHEMBL31473001

COc1cc(CO)ccc1S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

nearest known ligand 0.83

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 20/20 0.83
KAT7 O95251 19/20 0.83
KAT6B Q8WYB5 15/20 0.83
KAT5 Q92993 15/20 0.83
KAT8 Q9H7Z6 15/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31472954 0.95 KAT6A (0.88) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22828669 0.91 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26165840 0.91 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866152 0.90 KAT6A (0.83) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL31472950 0.90 KAT6A (0.83) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL22828704 0.90 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
Prifetrastat SCHEMBL29490368 0.90 KAT7 (0.90) KAT6AKAT7KAT6BKAT5KAT8
Prifetrastat SCHEMBL22802427 0.90 KAT7 (0.90) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL26165847 0.89 KAT7 (1.00) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL24866198 0.89 KAT6A (0.78) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098417-A1 SULFONAMIDE COMPOUND AND USE THEREOF 再和医药科技(苏州)有限公司 2025-05-15 WO disclosed