SCHEMBL31473289

SCHEMBL31473289

Cn1ncc2c(=O)n(Nc3ccc(F)cc3F)cnc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
BCDIN3D Q7Z5W3 2/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 3/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 9/20 0.39
ALDH1A2 O94788 4/20 0.39
ALDH1A3 P47895 4/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TP53 P04637 1/20 0.38
PIP4K2A P48426 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473323 0.86 MEN1 (0.47) NPC1RAB9ALMNAHPGDTSHR
SCHEMBL31473315 0.83 NPC1 (0.45) NPC1RAB9ALMNAHPGDTSHR
SCHEMBL31473320 0.80 MEN1 (0.40) NPC1RAB9ALMNAHPGDTSHR
SCHEMBL31473314 0.78 TP53 (0.52) NPC1RAB9ATSHRMEN1KMT2A
SCHEMBL31473297 0.77 SMN1; SMN2 (0.46) GAANPC1RAB9ALMNAHPGD
SCHEMBL31473285 0.77 KMT2A (0.47) NPC1RAB9ALMNATSHRMEN1
SCHEMBL31473322 0.77 KMT2A (0.47) NPC1RAB9ALMNAHPGDTSHR
SCHEMBL31473316 0.77 KMT2A (0.47) NPC1RAB9ALMNAHPGDTSHR
SCHEMBL31473303 0.75 MEN1 (0.53) NPC1RAB9ALMNAHPGDTSHR
SCHEMBL31473293 0.74 HAVCR2 (0.51) NPC1RAB9ALMNAHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390700-A Pyrazolopyrimidinone derivative containing aniline unit, and preparation method and application thereof 江苏海洋大学 2025-02-07 CN disclosed