SCHEMBL31474156

SCHEMBL31474156

Cc1nc(N=C=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 20/20 0.56
▸ PDGFRA P16234 13/20 0.56
▸ PDGFRB P09619 7/20 0.56
▸ FLT3 P36888 4/20 0.56
▸ CYP2C9 P11712 2/20 0.56
▸ KDR P35968 2/20 0.56
▸ KIT P10721 2/20 0.56
▸ LCK P06239 1/20 0.56
▸ PTK6 Q13882 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22729095 0.83 CSF1R (0.54) CSF1RPDGFRAPDGFRBFLT3KDR
SCHEMBL21425617 0.83 CSF1R (0.61) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL28341052 0.82 CSF1R (0.66) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL28893618 0.81 CSF1R (0.59) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL30022723 0.81 CSF1R (0.59) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL16028792 0.81 CSF1R (0.59) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL22729080 0.79 CSF1R (0.68) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL21426311 0.79 CSF1R (0.59) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL30086983 0.79 CSF1R (0.59) CSF1RPDGFRAPDGFRBFLT3CYP2C9
SCHEMBL16082679 0.78 CSF1R (0.67) CSF1RPDGFRAPDGFRBFLT3CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120004857-A CSF1R family inhibitor and application thereof in pharmacy 上海和誉生物医药科技有限公司 2025-05-16 — — CN disclosed
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