SCHEMBL31474537

SCHEMBL31474537

CC(C)(C)OC(=O)N1CCC(O)(c2nccnc2Cl)CC1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
OPRD1 P41143 1/20 0.43
OPRK1 P41145 1/20 0.43
GPR119 Q8TDV5 8/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
SYK P43405 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26105817 1.00 POLB (0.53) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL11989081 0.87 POLB (0.56) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL13474561 0.84 POLB (0.50) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL4013541 0.84 POLB (0.56) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL1303878 0.83 POLB (0.49) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL3249336 0.81 POLB (0.52) POLBOPRD1OPRK1GPR119SYK
SCHEMBL4282943 0.79 CCR1 (0.42) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL3436213 0.79 POLB (0.50) POLBOPRD1OPRK1GPR119SYK
SCHEMBL12178810 0.79 POLB (0.42) POLBOPRD1OPRK1GPR119MEN1
SCHEMBL3787005 0.79 POLB (0.50) POLBOPRD1OPRK1GPR119SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119403551-A Small molecule inhibitors of TEA domain family members 斯克里普斯研究学院 2025-02-07 CN disclosed