Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31474717 | 1.00 | TDP1 (0.57) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL1024936 | 0.83 | TDP1 (0.42) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL3816767 | 0.81 | TDP1 (0.66) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL258230 | 0.78 | TDP1 (0.68) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL29571308 | 0.78 | TDP1 (0.68) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL14081784 | 0.78 | TDP1 (0.57) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL9504678 | 0.77 | TDP1 (0.66) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1536025 | 0.77 | TDP1 (0.66) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL8691521 | 0.75 | KDM4C (0.50) | TDP1SIRT3KDM4CALDH1A1MAPT | |
| SCHEMBL29496054 | 0.74 | TDP1 (0.68) | TDP1SIRT3KDM4CALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707919-A | Deuterated piperazine compound and preparation method and application thereof | 山东大学 | 2025-03-28 | — | — | CN | disclosed |