SCHEMBL31474875

SCHEMBL31474875

N=c1oc2cc(F)c(F)cc2cc1C(N)=S

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPP5C P53041 1/20 0.59
MEN1 O00255 8/20 0.49
KMT2A Q03164 8/20 0.49
ALDH1A1 P00352 6/20 0.49
MAPT P10636 4/20 0.49
LCK P06239 2/20 0.42
GAA P10253 5/20 0.39
KDM4E B2RXH2 4/20 0.39
HPGD P15428 4/20 0.39
GLA P06280 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
S1PR4 O95977 1/20 0.39
MIF P14174 1/20 0.39
S1PR1 P21453 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
DNM2 P50570 2/20 0.36
NPC1 O15118 5/20 0.35
RAB9A P51151 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28987416 1.00 PPP5C (0.59) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL28987412 0.81 PPP5C (0.60) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL28987395 0.81 PPP5C (0.60) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL31474881 0.75 LCK (0.72) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL28987424 0.75 MEN1 (0.68) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL31474892 0.75 PPP5C (0.61) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL28987411 0.75 PPP5C (0.61) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL28987439 0.75 LCK (0.72) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL10812793 0.75 KMT2A (0.66) PPP5CMEN1KMT2AALDH1A1MAPT
SCHEMBL31474878 0.75 KMT2A (0.66) PPP5CMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974828-B Compounds as protein phosphatase 5 agonists, methods of preparation and uses thereof 中国药科大学 2025-02-11 CN disclosed