Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 13/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | FECH | P22830 | 1/20 | 0.46 |
| ▸ | MYH14 | Q7Z406 | 1/20 | 0.46 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.45 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888106 | 0.86 | ERBB2 (0.61) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL24569439 | 0.86 | ERBB2 (0.61) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL29887854 | 0.86 | ERBB2 (0.61) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL26893272 | 0.81 | EGFR (0.45) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL26893267 | 0.81 | EGFR (0.45) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL29309627 | 0.79 | MKNK2 (0.45) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL30050146 | 0.79 | ERBB2 (0.48) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL21886779 | 0.79 | ERBB2 (0.46) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL31377609 | 0.79 | EGFR (0.50) | EGFRERBB2NQO2FECHMYH14 | |
| SCHEMBL26428766 | 0.79 | ERBB2 (0.55) | EGFRERBB2NQO2FECHMYH14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129078-A1 | ERBB2 INHIBITORS | COGENT BIOSCIENCES, INC. | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129078-A1 | ERBB2 INHIBITORS | ERBB2, ERBB3, EGFR | EGFR 3/4885ERBB2 1/4885NQO2 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.