Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31477192 | 0.73 | IDO1 (0.46) | IDO1SMN1; SMN2HSD17B10KDM4EALOX15 | |
| SCHEMBL31477220 | 0.73 | BRD4 (0.42) | BRD4MAPK1 | |
| SCHEMBL31477306 | 0.73 | BRD4 (0.42) | BRD4MAPK1 | |
| SCHEMBL31477187 | 0.73 | GRIN2D (0.32) | CYP1A2HSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31477285 | 0.72 | GSK3B (0.43) | GSK3BIDO1TDO2CYP1A2SMN1; SMN2 | |
| SCHEMBL31477058 | 0.72 | GSK3B (0.43) | GSK3BIDO1TDO2CYP1A2SMN1; SMN2 | |
| SCHEMBL31477191 | 0.72 | GSK3B (0.43) | GSK3BIDO1TDO2CYP1A2SMN1; SMN2 | |
| SCHEMBL31477218 | 0.72 | GSK3B (0.43) | GSK3BIDO1TDO2CYP1A2SMN1; SMN2 | |
| SCHEMBL24086608 | 0.71 | PARP1 (0.56) | GSK3BPARP1CYP1A2SMN1; SMN2OTUD7B | |
| SCHEMBL31477518 | 0.71 | HSD17B10 (0.40) | GSK3BIDO1TDO2CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |