Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31477131 | 1.00 | GSK3B (0.40) | GSK3BTNKS2CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31477285 | 0.82 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31477058 | 0.82 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31477218 | 0.82 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31477191 | 0.82 | GSK3B (0.43) | GSK3BTNKS2CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31477193 | 0.79 | GSK3B (0.39) | GSK3BCYP1A2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31503084 | 0.77 | GSK3B (0.36) | GSK3BTNKS2CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL31477533 | 0.75 | TNKS2 (0.34) | GSK3BTNKS2AKT1 | |
| SCHEMBL31477284 | 0.75 | TNKS2 (0.34) | GSK3BTNKS2AKT1 | |
| SCHEMBL31477607 | 0.75 | TNKS2 (0.34) | GSK3BTNKS2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |