Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31481013 | 0.93 | KDR (0.49) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481173 | 0.92 | PIK3CG (0.42) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481125 | 0.89 | KDR (0.43) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481002 | 0.88 | PIK3CG (0.44) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481010 | 0.87 | PIK3CG (0.41) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481044 | 0.85 | CACNA1B (0.43) | KDRPIK3CGPIK3CD | |
| SCHEMBL31481238 | 0.85 | MEN1 (0.43) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481142 | 0.84 | PIK3CG (0.41) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31481051 | 0.84 | IKBKE (0.40) | KDRPIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31480977 | 0.83 | NTRK1 (0.38) | KDRPIK3CGPIK3CDPAK4JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |