Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25191133 | 0.84 | POLB (0.54) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL9983992 | 0.84 | MAPT (0.61) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL25197695 | 0.84 | POLB (0.67) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL6710563 | 0.81 | MAPT (0.58) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL1750127 | 0.81 | MAPT (0.58) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL6716676 | 0.81 | MAPT (0.58) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL3549925 | 0.81 | MAPT (0.58) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL12939934 | 0.81 | MAPT (0.58) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| Hydrochloric Acid SCHEMBL6707092 | 0.80 | MAPT (0.56) | POLBMAPTALDH1A1SIRT6ADRB1 | |
| SCHEMBL16943124 | 0.80 | MEN1 (0.60) | POLBMAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |