SCHEMBL31481900

SCHEMBL31481900

CCn1c(=O)n(-c2nnc(C(F)F)s2)c2cc(S(=O)(=O)Cl)cc(Br)c21

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31481727 0.82 PARG (0.57) PARG
SCHEMBL31481921 0.81 PARG (0.49) PARG
SCHEMBL31481731 0.81 PARG (0.58) PARG
SCHEMBL31481935 0.80 PARG (0.47) PARG
SCHEMBL31481913 0.79 PARG (0.46) PARG
SCHEMBL31481878 0.76 PARG (0.71) PARG
SCHEMBL31481930 0.74 PARG (0.53) PARG
SCHEMBL31481917 0.73 PARG (0.73) PARG
SCHEMBL31481932 0.72 PARG (0.44) PARG
SCHEMBL17845430 0.70 PARG (0.56) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025035108-A2 INHIBITORS OF PARG ARASE THERAPEUTICS INC. (US) 2025-02-13 WO disclosed