SCHEMBL31483045

SCHEMBL31483045

O=C(NCCOc1cccnc1)Nc1cc2cc(Br)ccn2n1

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 20/20 0.72
PIK3CA P42336 15/20 0.72
PIK3CD O00329 14/20 0.72
PIK3CB P42338 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31483100 0.88 PIK3CG (0.85) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31482999 0.84 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483003 0.83 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483120 0.82 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483005 0.81 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483072 0.80 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483011 0.80 PIK3CG (0.85) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483028 0.80 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31482994 0.79 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB
SCHEMBL31483020 0.78 PIK3CG (1.00) PIK3CGPIK3CAPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841829-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2025-04-18 CN disclosed