Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 11/20 | 0.57 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20836475 | 1.00 | GRM7 (0.57) | GRM7PDCD1CD274GABRA1GABRG2 | |
| SCHEMBL12643279 | 0.83 | GRM7 (0.45) | GRM7PDCD1CD274CRBNCYP2A6 | |
| SCHEMBL20836403 | 0.83 | GRM7 (0.48) | GRM7 | |
| SCHEMBL22257259 | 0.77 | GRM7 (0.71) | GRM7 | |
| SCHEMBL20836367 | 0.74 | GRM7 (0.50) | GRM7GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31483731 | 0.74 | GRM7 (0.50) | GRM7GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31483616 | 0.73 | GRM7 (1.00) | GRM7 | |
| SCHEMBL20836301 | 0.73 | GRM7 (1.00) | GRM7 | |
| SCHEMBL20836453 | 0.72 | GRM7 (0.81) | GRM7 | |
| SCHEMBL31483627 | 0.72 | GRM7 (0.81) | GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111148744-B | Novel heterocyclic compounds as MGLUR7 modulators | 布拉格玛治疗公司 | 2025-02-14 | — | — | CN | disclosed |