Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | WNT3 | P56703 | 1/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256527 | 1.00 | ACE (0.49) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL4174747 | 1.00 | ACE (0.49) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL713925 | 1.00 | ACE (0.49) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL926579 | 0.91 | HSD17B10 (0.43) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL9763240 | 0.91 | HSD17B10 (0.43) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL3617740 | 0.91 | HSD17B10 (0.43) | ACECHRM2CHRM1CHRM3WNT3 | |
| Propionaldehyde SCHEMBL6073504 | 0.90 | ACE (0.45) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL713924 | 0.87 | CHRM2 (0.41) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL12105456 | 0.87 | CHRM2 (0.41) | ACECHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL20345647 | 0.87 | CHRM2 (0.41) | ACECHRM2CHRM1CHRM3WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076476-A2 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |