Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 16/20 | 0.50 |
| ▸ | BRD4 | O60885 | 7/20 | 0.50 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.50 |
| ▸ | DCLK1 | O15075 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25935185 | 1.00 | PLK1 (0.50) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL30501236 | 1.00 | PLK1 (0.50) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL30501277 | 0.93 | PLK1 (0.50) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL25029398 | 0.93 | PLK1 (0.50) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL31405253 | 0.87 | PLK1 (0.60) | PLK1BRD4BRDT | |
| SCHEMBL30965740 | 0.86 | PLK1 (0.67) | PLK1BRD4BRDT | |
| SCHEMBL25024655 | 0.84 | PLK1 (0.53) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL30501239 | 0.84 | PLK1 (0.49) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL25935170 | 0.84 | PLK1 (0.49) | PLK1BRD4BRDTDCLK1LRRK2 | |
| SCHEMBL25031424 | 0.84 | PLK1 (0.60) | PLK1BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |