Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771633 | 1.00 | PARP1 (0.53) | PARP1KAT6AMEP1BIDH1CYP4F2 | |
| Hydrochloric Acid SCHEMBL27543812 | 0.98 | PARP1 (0.52) | PARP1KAT6AMEP1BIDH1CYP4F2 | |
| SCHEMBL5194309 | 0.89 | SPHK2 (0.52) | PARP1MEP1BIDH1CYP4F2CYP4A11 | |
| SCHEMBL10669113 | 0.88 | SPHK2 (0.57) | PARP1CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL28241905 | 0.86 | SPHK2 (0.60) | CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL15964806 | 0.86 | SPHK2 (0.60) | CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL9356792 | 0.86 | SPHK2 (0.60) | CYP4F2CYP4A11SPHK2SPHK1 | |
| SCHEMBL11050526 | 0.85 | KAT6A (0.50) | KAT6ACYP4F2CYP4A11FOLH1LOXL2 | |
| SCHEMBL11752450 | 0.85 | KAT6A (0.52) | KAT6ACYP4F2CYP4A11FOLH1LOXL2 | |
| SCHEMBL45866 | 0.85 | PARP1 (0.57) | PARP1KAT6AMEP1BIDH1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025058977-A1 | MODULATORS OF CORONAVIRUS 3C-LIKE PROTEASE AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2025-03-20 | — | — | WO | disclosed |