Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10257517 | 0.83 | CA12 (0.40) | CNKSR1ADORA3ADORA2AADORA1TTR | |
| SCHEMBL543224 | 0.83 | CA12 (0.40) | CNKSR1ADORA3ADORA2AADORA1TTR | |
| SCHEMBL544063 | 0.76 | CA12 (0.40) | CNKSR1ADORA3ADORA2AADORA1TTR | |
| SCHEMBL10258000 | 0.76 | CA12 (0.40) | CNKSR1ADORA3ADORA2AADORA1TTR | |
| SCHEMBL31487480 | 0.75 | — | — | |
| SCHEMBL31487821 | 0.75 | ADORA2A (0.36) | ADORA2AADORA1MAPTALDH1A1 | |
| SCHEMBL10257233 | 0.71 | NPC1 (0.44) | ADORA3ADORA2AADORA1TTRDPP4 | |
| SCHEMBL543543 | 0.71 | NPC1 (0.44) | ADORA3ADORA2AADORA1TTRDPP4 | |
| SCHEMBL3582253 | 0.70 | KDM4E (0.36) | TTRRAB9AMAPTMAOBALDH1A1 | |
| SCHEMBL31487459 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025058977-A1 | MODULATORS OF CORONAVIRUS 3C-LIKE PROTEASE AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2025-03-20 | — | — | WO | disclosed |